Neuvasq Biotechnologies is developing pharmaceuticals to sustain or restore neurovascular function, a novel mechanism to interfere with disease progression for the benefit of millions of patients affected by neurological disorders.
To help drive the development of its neurovascular/BBB-focused product pipeline, Neuvasq is looking for a (Senior) Research Associate, Cell Biology/Protein Chemistry.
The position is based in the Brussels South Charleroi Biopark, Belgium.
Key responsibilities:
- Support the development of cell-based assays or in vitro platforms that recapitulate various aspects of the biology of the blood-brain barrier.
- Express and purify engineered proteins for downstream evaluation.
- Evaluate compounds and molecules for their ability to interfere with pathways involved in the blood-brain barrier homeostasis.
- Contribute to the development of engineered cell lines to support assay development.
- Collaborate with other scientists for the design of in vivo studies aiming at the evaluation of selected molecules in relevant disease models.
Profile:
- Good knowledge of general molecular biology and cloning techniques, such as vector construction. Knowledge of CRISPR-Cas9 and/or lentiviral transfection is a plus.
- Practical experience in cell culture techniques, including ideally primary cells culture.
- Experience in vectors design and recombinant protein expression in eukaryotic systems.
- Hands-on experience in protein purification techniques such as affinity chromatography, IEX, HIC and SEC.
- Knowledge of general protein chemistry techniques, such as SDS-PAGE, western-blot, or ELISA. Experience with FACS or Biacore/Octet would be an additional asset.
- Well organized, flexible, and rigorous.
- Team-spirit oriented.
- Ability and willingness to learn.
- Previous experience in vivo animal studies and/or CNS biology is a plus.
- A BSc or MSc degree in biochemistry, biomedical engineering, molecular biology, chemistry, or similar fields.
- Considerable previous experience in a similar position is required.
Offer:
- A full-time contract in an exciting start-up environment.
- Close collaboration with a team of experts.
- A unique opportunity for personal development.
Cookie policy