Neuvasq Biotechnologies is a privately held Biotech company pioneering in the development of therapies to restore CNS barriers and improve neurovascular function
The Preclinical Research & Development Team is looking for a highly talented, motivated and driven Scientist who will report to the Head of the Preclinical Team and implement in vivo models of retinal and neurologic diseases driven by breakdown of the blood-retinal and blood-brain barrier. The successful candidate will have a strong scientific background in ophthalmology and/or neurology, and experience with small animal models of disease. The position also involves collaboration with external academics and contract research organizations to accelerate the development of new therapies.
The position represents an outstanding opportunity for a talented in vivo scientist to transform groundbreaking research into new therapies for people living with neurovascular diseases with high unmet medical need. The candidate should have an inquisitive, dynamic and co-operative nature with a rigorous approach to data generation.
The position is based in the Brussels South Charleroi Biopark, Belgium.
Key responsibilities:
- Implementation of in vivo assays of blood-retinal and blood-brain barrier permeability in small animals
- Implementation of in vivo small animal disease models of retinal and neurologic diseases to test novel drug candidates
- Design and hands-on execution of in vivo/ex vivo experiments to provide key data that will support timely decision making and preclinical regulatory packages.
- Develop deep understanding of the target biology to successfully achieve the above objective.
- Compile, summarize and critically analyze data and present them at project team meetings.
- Maintain good interaction with personnel in the animal facility to facilitate smooth execution of experiments
- Provide high quality documentation (procedures, protocols, reports) of all technical work performed in the lab using an electronic reporting system
- Demonstrate strong project ownership, pro-active problem solving and a willingness to stay with problems until solutions are found.
- Stay up to date with the target literature and new developments in the subject area.
- Actively contribute to lab management as required.
Profile:
- PhD in Neurosciences or related field.
- FELASA B certificate or higher
- Strong track record of scientific publications or productivity
- Hands-on experience of working with rodent animal models of retinal or neurologic disease
- Surgical/microsurgical skills and experience in rodents. Experience with retinal disease models, intravitreal and subretinal injection, stroke and/or epilepsy models is a plus
- Committed to rigorous data generation, analysis and interpretation and passionate about science.
- Excellent interpersonal and communication skills.
- Dedicated and detail-oriented, strong sense of time management and a good ability to adapt to changes in priorities and thrive in a fast-paced and dynamic work environment.
- Excellent command of English (oral and written).
Offer:
- The challenge and excitement of an expanding start-up
- Close collaboration with the founders and a great international team of experts in science
- The possibility to boost your experience and career
- You will join a highly motivated, international and dynamic team
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