Neuvasq Biotechnologies is a privately held Biotech company pioneering in the development of therapies to restore CNS barriers and improve neurovascular function
The Research & Development Team is looking for a highly talented, motivated and driven Senior Research Associate who will support the development of cell-based assays or in vitro platforms and evaluate new molecules for their ability to engage pathways involved in the blood-brain or blood-retinal barriers homeostasis.
The position is based in the Brussels South Charleroi Biopark, Belgium.
Key responsibilities:
- Support the development of cell-based assays or in vitro platforms that recapitulate various aspects of the biology of the blood-brain or blood-retinal barriers.
- Design, express and purify engineered proteins for downstream evaluation.
- Evaluate molecules for their ability to interfere with pathways involved in the blood-brain or blood-retinal barriers homeostasis.
- Contribute to in vivo studies aiming at the evaluation of selected molecules in relevant neurovascular disease models.
- Report to Senior Scientists and Head of Drug Discovery or Preclinical Development
Profile:
- A master’s degree in Biochemistry, Biomedical engineering, Molecular biology, Chemistry, Life science.
- FELASA B certificate.
- Previous experience in a similar position is required.
- Good knowledge of general molecular biology and cloning techniques, including vector construction.
- Practical experience in cell culture techniques, including ideally primary cells culture.
- Experience in vectors design and recombinant protein expression in eukaryotic systems.
- Hands-on experience in protein purification techniques such as affinity chromatography, IEX, HIC and SEC.
- Knowledge of general protein chemistry techniques, such as SDS-PAGE, western-blot, or ELISA. Experience with FACS would be an additional asset.
- Demonstrated experience in handling, injecting and dissecting mice (and rats).
- Demonstrated experience with tissue sectioning, histology, and/or Immunohistochemistry.
- Previous experience with in vivo animal studies of CNS biology is a plus.
- Well organized, flexible, and rigorous.
- Team-spirit oriented and ability and willingness to learn.
- French speaking environment but a good knowledge of English is recommended.
Offer:
- A stimulating position within a high-potential innovative biotech company.
- The opportunity to work in a science-driven, dynamic, respectful, and professional team.
- A challenging scientific and business growth in which you get to bring your skills.
- A permanent contract with an attractive salary package in line with the position responsibilities and your experience.
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